RAF Typhoon FGR4s have conducted a mission with French warplanes in a joint strike on an underground arms cache in Syria operated by the Daesh militant organization, according to the UK's MoD.
The site, located using surveillance, was thought to be containing munitions and bombs, the announcement noted, and was located in mountains just above Palmyra in the heart of Syria.
"The RAF jets utilized precision-guided Paveway IV munitions to strike a several approach shafts down to the site... preliminary assessments are that the objective was successfully hit," officials stated.
There was no indication of any civilian impact in the strike conducted Saturday night and every plane involved made a safe return, the ministry further stated.
The Typhoon fighters were assisted by a Voyager refuelling tanker.
The Islamic State group - alternatively referred to as ISIS - established extremist governance over large swathes of Iraq and Syria until 2019.
"This operation shows British leadership, and resolve to operate in unison with our allies, to eliminate any resurgence of the terrorist group and their violent and radical beliefs in the Middle East," UK Defence Secretary the Defence Secretary stated.
British military aircraft have conducted surveillance missions over Syria to "prevent any attempted comeback" of Islamic State following its military defeat at the Baghuz confrontation in the year 2019, the ministry said.
"I must thank every member of the UK armed forces who took part in this operation for their skill and their courage," the Defence Secretary commented. "They were among thousands of UK service members on duty over the holidays. This operation, to take out dangerous terrorists who endanger our way of life, demonstrates how UK forces are always on standby, continuously, ensuring Britain's security domestically and influential overseas."
In December, the US military carried out what it termed a "massive strike" against IS targets in the country, after an attack resulted in the deaths of two American soldiers and a civilian interpreter in Palmyra.
The United Nations estimates IS still maintains between 5,000 and 7,000 combatants in Syria and Iraq.